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TRANSCEND trial meets primary endpoint with -19.8% placebo-adjusted BMI reduction in patients with acquired hypothalamic obesity
Rhythm Pharmaceuticals has announced positive topline results from the pivotal Phase 3 TRANSCEND trial evaluating setmelanotide, a...
MC4R Agonist bremelanotide co-administered with tirzepatide meets primary endpoint
Palatin Technologies’ BMT-801 Phase 2 obesity co-administered melanocortin-4 receptor (MC4R) agonist bremelanotide plus glucagon like...
Palatin completes Phase 2 obesity study with MC4R bremelanotide + Tirzepatide
Palatin Technologies has completed its Phase 2 BMT-801 clinical study of the co-administration of MC4R bremelanotide + GLP-1/GIP...
Neurons that control the amount of MC4R affect how much the protein guards against obesity
Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study...
Palatin completes study enrolment of bremelanotide plus tirzepatide to treat obesity
Palatin Technologies has completed enrolment in the study entitled "BMT-801, A Phase II, Randomized, Double-Blind, Placebo-Controlled,...
Middle-age obesity may be caused by changes in the shapes of neurons in the brain, impacting the role of MC4Rs
Middle-age obesity is caused by age-related changes in the shape of neurons in the hypothalamus, a region of the brain that controls...
Palatin to investigate MC4R agonist as a potentially effective and safe treatment for obesity
Palatin Technologies, a biopharmaceutical company developing first-in-class medicines based on molecules that modulate the activity of...
Examining how endogenous cannabinoids regulate body weight
Researchers from the Warren Center for Neuroscience Drug Discovery have discovered how endogenous cannabinoids, those made by the body,...
Visualising structure of MC4R protein could aid obesity treatments
Researchers from Charité – Universitätsmedizin Berlin, Germany, have visualised the 3D molecular structures of the hormones with which a...
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