MBS associated with favourable short‑ to mid‑term safety outcomes and improvements in weight and obesity‑related comorbidities in adolescents

Metabolic and bariatric surgery (MBS) can be delivered safely and effectively for adolescents and young adults living with severe obesity, offering promising improvements in weight loss and obesity-related health conditions, according to a study by researchers from LSU's Pennington Biomedical Research Center, FMOL Health | Our Lady of the Lake Regional Medical Center and Metamor Institute.

The study examined outcomes from 76 patients ages 10–25 who underwent bariatric surgery between January 2020 and March 2025 through a Louisiana-based bariatric surgery program at the Metamor Institute. Researchers evaluated both safety outcomes and longer-term health improvements, helping expand understanding of how surgical obesity treatment can benefit younger populations.

Philip Schauer

"Our findings suggest metabolic and bariatric surgery can be performed safely and effectively in young patients when delivered through a comprehensive, multidisciplinary care model," said Dr Philip Schauer, United Companies Life Insurance Co/Mary Kay and Terrell Brown chair at Pennington Biomedical and director of the Metamor Institute. "This study reflects the importance of carefully selecting patients, matching them with the most appropriate procedure and surrounding them with coordinated clinical support to help achieve the best possible outcomes."

Among the study's key findings:

• Patients achieved an average of 29–32% total body weight loss, maintained over one to five years.

• Among patients with available follow-up, 94% experienced remission of type 2 diabetes, 67% showed improvement in hypertension and dyslipidaemia, and 64% experienced improvement in gastroesophageal reflux disease (GERD).

• Surgical complications remained low, with only 5% experiencing complications within 30 days.

Importantly, the study population represented a broad cross-section of Louisiana patients, with nearly 75% covered through Medicaid insurance, underscoring the need to ensure access to advanced obesity treatment options regardless of socioeconomic background.

"The American Academy of Pediatrics (AAP) recommends that adolescents aged 13 and older with severe obesity (BMI >35 with at least one major comorbidity) be evaluated for metabolic and bariatric surgery, shifting from 'watchful waiting' to earlier, more intensive treatments," said Dr Katie Queen of Our Lady of the Lake Children's Hospital. "The AAP also recommends that these procedures be performed by experienced bariatric surgeons and combined with comprehensive nutritional support and behavioural therapy."

The researchers note that successful outcomes were likely driven by the coordinated care model established through the collaboration of Pennington Biomedical, Our Lady of the Lake and Metamor Institute, bringing together leading expertise in obesity research, clinical medicine and bariatric surgery.

"Severe obesity is a complex chronic disease that often begins early in life and can rapidly lead to serious long-term health complications," said Dr Vance Albaugh, assistant professor of metabolic surgery at Pennington Biomedical. "These findings provide encouraging evidence that with the right multidisciplinary approach, surgery can play an important role in improving health outcomes for younger patients while also reinforcing the need for continued research to better guide care decisions for this population."

The findings were reported in the paper, ‘Outcomes of Metabolic and Bariatric Surgery Among Adolescents and Young Adults in Southern Louisiana’, published in Obesity. To access this paper, please click here