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Metabolic and bariatric surgery after GLP-1s use results in greater weight loss vs medication alone
People who begin obesity treatment with glucagon-like peptide-1 receptor agonists (GLP-1s) and then undergo metabolic and bariatric surgery achieve substantially greater weight loss than with the medications alone, according to research, ‘Bariatric surgery effectiveness after glp-1 agonist weight loss (abstract id: 4149)’, presented at the annual meeting of the American Society for Metabolic and Bariatric Surgery. “Patients are increasingly having surgery after GLP-1 therapy,


Maintaining weight loss after bariatric surgery more difficult due to fat cells' 'memory' of prediabetes
Prediabetes may leave a lasting molecular "footprint" on adipose (fat) tissue which appears to make maintaining weight loss after bariatric surgery more difficult, according to new research being presented at the European Congress on Obesity (ECO) in Istanbul, Turkey. "Our findings suggest that prediabetes is associated with persistent changes in fat tissue that may limit its ability to fully adapt after weight loss," said author, Dr Camila Milad from Hospital Clinic de Barce


ATLAS study: How weight loss benefits the health of fat tissue
A study led by Assistant Professor Anne Loft, Associate Professor Jesper Grud Skat Madsen and Professor Susanne Mandrup from University of Southern Denmark sheds light on what happens in the fat tissue during weight loss. All three are leading researchers at the Center of Excellence ATLAS, which investigates the molecular mechanisms driving changes in liver and fat tissues in response to obesity and weight loss. This knowledge is important because obesity-induced dysfunction


MBS for weight loss shows greater long-term benefits than GLP-1 medicines
A large Cleveland Clinic study has found that people with obesity and type 2 diabetes who undergo metabolic and bariatric surgery (MBS)...


Weight loss clears out aging cells and boosts lipid recycling
Researchers from the Medical Research Council (MRC) Laboratory of Medical Sciences and Imperial College London, UK, have produced the...


Tailoring the dose of botulinum toxin and refining the injection technique is safe and effective for patients living with obesity
Gastric botulinum therapy using a novel full-stomach injection method focusing on the antrum and fundus is safe and effective in Japanese...


raRYGB can be a potent and safe option for standard practice
Roux-en-Y gastric bypass (raRYGB) with the MiniMIZER gastric ring (Bariatric Solutions International) resulted in enhanced weight loss...


Ratioing the resected gastric volume to the number of fired staplers predicts weight loss
Ratioing the resected gastric volume (RGV) to the number of staplers fired (SF) could be used to predict midterm weight loss, according...


Liraglutide after RYGB results in significant weight loss and resolution of obesity-related conditions
Adjunctive use of liraglutide at a dose of 3mg/day with conversional Roux-en-Y Gastric Bypass (cRYGB) results in significant weight loss,...


GLP-1 RAs show cardiovascular benefits beyond weight loss
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) continue to show cardiovascular benefits beyond weight loss, according to several...
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