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Tirzepatide does not just help people lose weight, but it also activates brown adipose tissue, representing a major milestone in obesity research, according to a study presented at ENDO 2026, the Endocrine Society's annual meeting in Chicago. "In the TABFAT trial, we asked a different question: Beyond eating less, does tirzepatide also change how the body burns energy - specifically through brown adipose tissue, a metabolically active type of fat that produces heat and consum

A study led by the University of Barcelona has identified a key molecular mechanism in the loss of brown fat activity during ageing. The study opens up new perspectives for designing strategies to boost the activity of this tissue and prevent chronic metabolic and cardiovascular diseases as the population ages. From left to right, Tania Quesada-López, Francesc Villarroya, Albert Blasco-Roset, Marta Giralt, Alberto Mestres-Arenas, Joan Villarroya, Aleix Gavaldà-Navarro and Rub