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Endoscopic sleeve gastroplasty (ESG) is associated with significantly greater short-term weight loss than oral semaglutide in adults with obesity, according to the outcomes from a comparative study, ‘Endoscopic Sleeve Gastroplasty Versus Oral Semaglutide for Obesity: A Real World Comparative Study’, presented at the European Society of Gastrointestinal Endoscopy (ESGE) Days 2026. Endoscopic sleeve gastroplasty is a minimally invasive endoscopic procedure that reduces gastric