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Stigma toward women who lose weight using GLP-1 medications is greater compared to weight loss via diet and exercise
Women who lost weight using GLP-1 medications are judged more harshly than those who lost weight through diet and exercise, with negative reactions driven largely by beliefs that medication-assisted weight loss is a ‘shortcut’, according to a study by Georgetown University Medical Center researchers. The study also found higher levels of stigma when the women in sample scenarios were portrayed as white rather than Black. The findings highlight how social narratives about ‘acc


Genetic variants may reduce blood‑sugar response to GLP‑1 diabetes drugs
More than a quarter of people with Type 2 diabetes take glucagon-like peptide-1 (GLP-1), but the popular diabetes drugs might not work as well for people who have certain genetic variants, according to a study by Stanford Medicine scientists and their collaborators. The genetic variants, carried by roughly 10% of the general population, cause a surprising and still mysterious phenomenon that researchers refer to as GLP-1 resistance, in which levels of the hormone GLP-1, which


Rise in GLP-1 treatment for bariatric surgery-eligible patients
According to researcher from Ohio State University Wexner Medical Center in Columbus, prescription for patients who were eligible for metabolic and bariatric surgery (MBS) for glucagon-like peptide-1 receptor agonist (GLP-1 RA) increased from 2018 to 2025, while MBS use decreased beginning in 2023. “To our knowledge, this is the first study to provide evidence that trends in MBS use have not yet stabilised through quarter 3 of 2025,” the researchers noted. “Stratification by


WHO issues global guideline on the use of GLP-1 medicines
The World Health Organization (WHO) has released its first guideline on the use of Glucagon-Like Peptide-1 (GLP-1) therapies for treating obesity as a chronic, relapsing disease, to address the growing global health challenge of obesity that affects more than one billion people. In 2024, obesity was associated with 3.7 million deaths worldwide and without decisive action, the number of people with obesity is projected to double by 2030. In September 2025, WHO added GLP-1 ther
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