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Miboko app resulted in greater engagement levels and sustainable weight reduction

Nemaura Medical has announced that interim results from its metabolic health program - established to assess whether a metabolic program with a daily wear continuous glucose monitoring (CGM) worn twice a month - resulted in greater engagement levels and sustainable weight reduction. The multi-centred study was run in collaboration with the UK's National Health Service.

Miboko

Known as Miboko (Mind, Body, Konnect), the program is the first to integrate a daily-wear and non-invasive glucose sensor with the Nemaura’s bespoke app, educational content and AI driven analytics platform.


Users were invited to participate by their primary care practice, based on a BMI>25. None of those invited to participate had expressed a willingness to join a metabolic weight loss program or had previously heard of the Miboko program. Participants used the Miboko app and were given access to relevant education modules relating to aspects of metabolic health and weight loss.

Diet and lifestyle were entered daily into the app and weight was recorded weekly. Every two weeks, users wore the daily wear continuous glucose sensor, which tracked and displayed real-time glucose. At the end of the day, participants were provided with a Metascore and measure of glucose variability.


In addition, users were presented with a video report which analysed their glucose trends and made diet and lifestyle recommendations. The Metascore is derived from a number of factors including BMI, insulin sensitivity and lifestyle.

The study tracked 83 participants, with a mean age of 54 years old. The cohort was made up of 67% female (F), and 33% male (M), and 88% of participants recorded their ethnicity as 'White'. After 20 weeks of enrolment, 59 people (16M/43F) had recorded weight loss, with 21 participants losing over 5KG (11 pounds). On an average basis, weight loss was 2.9KG (6.3 pounds) (1.9M/3.2F), with the rate of change increasing after week 8.


Qualitative feedback from users demonstrated substantially increased levels of understanding and empowerment on their weight loss goals, correlating to long-term behavioural changes that are pivotal to sustained weight loss. Of particular note is that users derived considerable benefit from their personalised insights, based on their Metascore and response to diet and exercise. Verbatims from users confirmed that CGM sensor use increased user participation, better understanding of food choices and portion size.


After 20 weeks of use, the program had a retention rate of 32.5%. When active participants were asked whether they would continue with the program, 64% of respondents stated they were likely or very likely to continue to use the program. According to the company, this far exceeds retention rates for health and wellbeing apps of 16.7% at 13 weeks and 6.9% at 26 weeks.


Published studies report that affordability is a key barrier to CGM adoption, and the company aims to price its CGM-embedded program significantly lower than any presently available comparable program.


The integration of Nemaura's CGM sensor means that for the first time, a low-cost metabolic health improvement prevention program will soon be commercially available. The company has the advantage of its own proprietary non-invasive sensor technology, which significantly reduces sensor costs, as the sensors are only worn a few days each month.

The Company plan to publish more detailed results in due course.

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