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Researchers uncover mechanism explaining how obesity increases cancer risk
Scientists at City of Hope and TGen (part of City of Hope) have explained a major mechanism for why gaining excess weight increases the risk of cancer across multiple organs. The findings emphasise the importance of maintaining a healthy weight from early childhood and propose a potentially more accurate way than body mass index (BMI) to predict the increase in cancer risk associated with obesity. "People have long been told that obesity increases cancer risk, but they are ra


Magnetic compression simplifies revisional sleeve gastrectomy
The preliminary findings from a multi-centre study assessing magnetic gastroileostomy bipartition (MagGI procedure) as a revisional option for suboptimal sleeve gastrectomy (SG), suggest that SG-revisional MagGI was technically feasible and achieved promising excess weight loss of 66.0%. Self-aligning GT Metabolic MagDI System magnets fused together The study was conducted in adults (body mass index [BMI, kg/m2] ≥30.0–≤50.0). The 90-day primary feasibility endpoint was magnet


GLP-1s may affect some complications after panniculectomy
For patients undergoing body contouring surgery to remove excess abdominal skin after significant weight loss, use of GLP-1 weight-loss medications may have mixed effects on complication risks, according to a study by researchers from West Virginia University School of Medicine, Morgantown, WV. Share of all patients who take a GLP-1 RA by state. Credit: Plastic & Reconstructive Surgery (2025). DOI: 10.1097/prs.0000000000012405 "As GLP-1 receptor agonist (GLP1ra) medications b


Broward Health surgeon achieves milestone with 2,555 robotic-assisted procedures
Dr Alexander Parr, a board-certified general and bariatric surgeon with the Broward Health Physician Group, has reached a milestone achievement, performing his 2,555th robotic-assisted procedure using the Da Vinci Surgical System at Broward Health Imperial Point, marking a significant landmark in his career and underscoring Broward Health’s commitment to advanced surgical technology. Alexander Parr “Reaching 2,555 robotic-assisted procedures is an exciting milestone, but more


Amylyx completes LUCIDITY Clinical Trial enrolment assessing avexitide for post-bariatric hypoglycemia
The last participant has been randomised and dosed in Amylyx Pharmaceuticals’ pivotal Phase 3 LUCIDITY clinical trial of avexitide, an investigational, first-in-class glucagon-like peptide-1 (GLP-1) receptor antagonist with an FDA Breakthrough Therapy Designation in post-bariatric hypoglycemia (PBH). LUCIDITY is a 16-week, multicentre, randomised, double-blind, placebo-controlled trial evaluating the efficacy and safety of avexitide in adults with PBH following Roux-en-Y gast


RYGB and SADI-S are effective and safe revisional options after SG
Both Roux-en-Y gastric bypass (RYGB) and single-anastomosis duodeno-ileal bypass (SADI-S) are effective and safe revisional options after sleeve gastrectomy (SG), according to researchers from Hamad Medical Corporation, Doha, Qatar. They noted that SADI-S offers superior long-term weight-loss and metabolic outcomes, whereas RYGB remains preferable for patients with significant or persistent GERD. “Tailoring revisional procedure selection to patient characteristics and ensurin
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