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Loose fundoplication utilising the excluded stomach into OAGB improves HRQoL vs OAGB alone
The combination of a loose fundoplication utilising the excluded stomach into one-anastomosis gastric bypass (OAGB) demonstrates a notable enhancement in HRQoL compared with OAGB alone, for patients experiencing obesity and significant reflux. According to the study’s authors by researchers from Homerton University Hospital, London and Ain Shams University, Cairo, this combined approach yielded lower GERD-Health-Related Quality of Life (GERD-HRQL) scores (indicating improved


semaglutide could help dialysis patients qualify for kidney transplants
New research from Saint Louis University School of Medicine and SSM Health has revealed weight loss medications could help dialysis patients qualify for kidney transplants. The study is among the largest to examine semaglutide in dialysis patients. These individuals are often excluded from transplant waitlists because a high body mass index (BMI) increases surgical risks and impacts outcomes after transplantation. Key findings: Patients lost an average of 20.5 pounds after on


Vanda’s Tradipitant prevents GLP-1 induced nausea and vomiting
Vanda Pharmaceuticals has announced positive topline results from its randomised controlled clinical study (VP-VLY-686-2601) evaluating tradipitant, an oral neurokinin-1 (NK-1) receptor antagonist, for the prevention of nausea and vomiting induced by GLP-1 receptor agonist Wegovy in overweight and obese adults. This study, which pre-treated patients with either tradipitant or placebo before administering a 1 mg injection of Wegovy, a dose that normally takes 9 weeks of titrat


Conversional bariatric surgery seems to be increasing in incidence in adults under 40
In a large retrospective study using the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database, conversional bariatric surgery seems to be increasing in incidence in adults under 40, with notable differences in baseline characteristics of patients undergoing different conversional procedures as well as the reasons for conversion. The study, carried out by researchers from the University of Alberta, Edmonton, Alberta, Canada, to under


Hypertension in children and adolescents nearly doubled between 2000 and 2020
The rate of children and adolescents experiencing high blood pressure worldwide nearly doubled between 2000 and 2020, according to a new meta-analysis by researchers from China and the UK. In 2000, approximately 3.2% of children had hypertension, but by 2020, the prevalence had increased to more than 6.2% of children and adolescents under age 19, affecting 114 million young people around the world. The study suggests that obesity is a substantial driver of the increase in chi


Ultra-processed food intake linked to prediabetes in young adults
Researchers at the Keck School of Medicine of USC have completed one of the first studies to examine the link between ultra-processed foods (UPFs) consumption and how the body processes glucose, which is known to predict diabetes risk. By tracking changes over time, they gained insights into how dietary choices may influence key biological processes. More than half of calories consumed in the United States come from UPFs, items like fast food and packaged snacks that are ofte
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