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CagriSema associated with significant reduction in blood pressure and reduces the proportion of patients at risk of developing heart disease
Post hoc analyses from the phase 3 REDEFINE 1 trial evaluating CagriSema, an investigational injectable combination treatment for adults with overweight or obesity, and its effects on well-known cardiovascular (CV) risk factors, has revealed that systolic blood pressure was reduced by -10.9 mmHg over 68 weeks (versus -8.8 mmHg with semaglutide 2.4 mg and -2.1 mmHg with placebo). This reduction was seen regardless of BMI (less than versus greater than or equal to 35 kg/m2). In


REDEFINE 1 trial: CagriSema results in 22.7% mean weight reduction in adults with overweight or obesity
Outcomes from Novo Nordisk's phase 3 REDEFINE 1 trial - evaluating the efficacy and safety of investigational CagriSema plus lifestyle...


REDEFINE 2: CagriSema demonstrates superior weight loss
Outcomes from the from REDEFINE 2, a phase 3 trial in the global REDEFINE programme, have revealed the trial achieved its primary...


REDEFINE 1 trial: CagriSema demonstrates superior weight loss in adults with obesity or overweight
Headline results from Novo Nordisk’s REDEFINE 1 has shown that the trial achieved its primary endpoint by demonstrating a statistically...


Novo Nordisk to initiate study assessing CagriSema vs Tirzepatide
Novo Nordisk is planning a study that will see CagriSema, a new investigational medicine developed by Novo that combines Cagrilintide and...
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