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FDA approves Wegovy for MASH with moderate to advanced liver fibrosis
The FDA has approved Wegovy (semaglutide) injection 2.4 mg to treat adults with MASH with moderate to advanced liver scarring (fibrosis),...


Endoscopic sleeve gastroplasty an effective alternative therapy for MASH
Endoscopic sleeve gastroplasty (ESG) may be an effective alternative therapy in the treatment of patients with metabolic...


D&D Pharmatech completes enrolment in trial evaluating DD01 Dual GLP-1/Glucagon receptor agonist for MASH
D&D Pharmatech has completed patient enrolment in DD01-DN-2, an ongoing Phase 2 trial designed to evaluate the efficacy and safety of...


ESSENCE trial: Semaglutide 2.4mg demonstrates statistically significant and superior improvements with in people with MASH
Results from part 1 of the ongoing Phase 3 ESSENCE trial - evaluating the effect of once-weekly subcutaneous semaglutide 2.4mg on liver...


FDA grants Breakthrough Therapy designation for Zealand Pharma’s survodutide
The FDA has granted Breakthrough Therapy designation to Zealand Pharma’s survodutide (BI 456906), a dual glucagon/GLP-1 receptor agonist...


Blocking circulating protein interferon-γ pathway could lead to potential treatment for metabolic liver disease
University of Massachusetts Medical School researchers have identified a novel pathway in the progression of metabolic liver disease that...


Journal Watch 12/06/2024
Welcome to our weekly round-up of the latest bariatric and obesity-related papers published in the medical literature. As ever, we have...


Tirzepatide was superior to placebo for MASH resolution
Results from Eli Lilly and Company’s SYNERGY-NASH that evaluated the investigational use of tirzepatide in adults with biopsy-proven...


Phase 2 trial shows 83% of adults treated with survodutide achieve significant improvement in MASH
Up to 83.0% of adults treated with survodutide (Boehringer Ingelheim and Zealand Pharma) achieved a statistically significant improvement...
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