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Study finds bariatric surgery less costly than GLP-1s over time
A new real-world analysis of more than 90,000 patients with obesity and type 2 diabetes finds metabolic and bariatric surgery is costs significantly less than weekly injections of GLP-1 drugs over a two-year period, according to research, ‘Understanding insurance-based differential healthcare costs for GLP-1ra versus bariatric surgery (abstract id: 4339)’, presented at the annual scientific meeting of the American Society for Metabolic and Bariatric Surgery. “As GLP-1 use bec


Bariatric surgery more effective than GLP-1s at preventing MACE in older patients
Metabolic and bariatric surgery offers significantly greater long-term protection against major adverse cardiovascular events (MACE, eg heart attack, stroke) and death than GLP-1 drugs in older adults with obesity and diabetes, according to real-world analysis study, ‘Cardiometabolic outcomes of metabolic surgery versus GLP-1 receptor agonists in older adults with diabetes and obesity (Abstract ID: 4719)’, presented at the annual meeting of the American Society for Metabolic


Most weight loss achieved using injectable obesity drugs can be maintained by switching to orforglipron
Most weight loss achieved using the injectable obesity drugs tirzepatide or semaglutide can be maintained by switching to daily oral orforglipron treatment, accord to research presented at the European Congress on Obesity in Istanbul, Turkey. The study is by Dr Louis J Aronne, Director of the Comprehensive Weight Control Center at Weill Cornell Medicine, New York, NY, and colleagues. While the efficacy of injectable therapies has been repeatedly proven in clinical trials, how


Surgery and drugs outperform diet and exercise for fat-free mass loss
A systematic review and meta-analysis of studies, ‘Effects of Incretin-Based Therapies, Diet and Exercise interventions, and Bariatric Surgery on Fat-Free Mass in Adults with Overweight or Obesity: A Systematic Review and Meta-Analysis’, presented at the European Congress on Obesity in Istanbul, Turkey, shows that diet and exercise interventions result in a lower proportion of fat-free mass loss compared with bariatric surgery or obesity drugs among people undergoing a weight


BMI classification system wrongly identifies some people as having overweight or obesity
Research from Italy presented at this year's European Congress on Obesity, Istanbul, Türkiye, shows that when the gold standard technique of dual-energy X-ray absorptiometry (DXA) is used to measure body fat in the general population, it shows that the traditional WHO body mass index (BMI) classification system misidentifies significant numbers of people as having overweight or obesity. In the past few years there has been a lot of criticism of the BMI system due to its inabi


Surgery dramatically reduces risk of kidney failure
Metabolic and bariatric surgery dramatically improves outcomes for patients with obesity and chronic kidney disease (CKD), significantly reducing the risk of kidney failure, major cardiovascular events (MACE) and death, according to research, ‘Long-term renal and survival outcomes in patients with obesity and chronic kidney disease following metabolic and bariatric surgery: A Trinetx cohort study (Abstract ID: 4520)’ presented at the annual meeting of the American Society for


Study shows association between OSA, all-cause mortality and cardiovascular events
Research presented at this year’s European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12-15 May) shows that those living with obstructive sleep apnoea (OSA) have a 71% higher risk of cardiovascular events (CVEs) or death from any cause (all-cause mortality) compared with those not living with OSA. OSA is characterised by recurrent upper airway obstruction during sleep and is associated with reduced quality of sleep and life and increased cardiovascular risk. The preval


PADRIAC project: Ten-year trial testing GLP-1 drugs to prevent obesity-related cancers
A global panel of 21 obesity and cancer experts have suggested that to test the potential efficacy of the new generation of obesity drugs such as semaglutide and tirzepatide in preventing obesity-related cancer (ORC), a trial of the drugs for some 5,000 participants at high risk of cancer due to their having a cancer pre-cursor condition will provide the required answers. The group of experts, convened at the European Congress on Obesity (ECO2026) in Istanbul, Turkey, includi


Heart, metabolic and inflammatory risk patterns differ between men and women with obesity
Research from Italy presented at this year's European Congress on Obesity, Istanbul, Türkiye, shows that when the gold standard technique of dual-energy X-ray absorptiometry (DXA) is used to measure body fat in the general population, it shows that the traditional WHO body mass index (BMI) classification system misidentifies significant numbers of people as having overweight or obesity. In the past few years there has been a lot of criticism of the BMI system due to its inabi


Maintaining weight loss after bariatric surgery more difficult due to fat cells' 'memory' of prediabetes
Prediabetes may leave a lasting molecular "footprint" on adipose (fat) tissue which appears to make maintaining weight loss after bariatric surgery more difficult, according to new research being presented at the European Congress on Obesity (ECO) in Istanbul, Turkey. "Our findings suggest that prediabetes is associated with persistent changes in fat tissue that may limit its ability to fully adapt after weight loss," said author, Dr Camila Milad from Hospital Clinic de Barce
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