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Lilly’s oral GLP-1 orforglipron shows meaningful weight loss and cardiometabolic improvements
Results from the Phase 3 ATTAIN-1 trial, evaluating the safety and efficacy of orforglipron, an investigational oral glucagon-like...


Semaglutide protects against diabetic retinopathy
GLP-1 receptor agonist drugs protect against diabetic retinopathy, a common complication of diabetes that can lead to sight loss,...


MBS for weight loss shows greater long-term benefits than GLP-1 medicines
A large Cleveland Clinic study has found that people with obesity and type 2 diabetes who undergo metabolic and bariatric surgery (MBS)...


GLP-1 drugs shown cost-effective for knee osteoarthritis and obesity, but MBS may be the best option from a clinical and economic perspective
A study led by investigators at Mass General Brigham has found that adding semaglutide and tirzepatide to usual care represents a...


Taking semaglutide reduces ‘food noise’
Individuals who are taking semaglutide for weight loss experience less food noise than before, according to research presented at the...


One in five people taking GLP-1s claim food tastes saltier or sweeter than before
Some individuals who are taking Ozempic, Wegovy or Mounjaro find that foods taste sweeter or saltier than before, according to research...


Genetic variants explain why obesity affects people differently
An international team of researchers led by Icahn School of Medicine at Mount Sinai and the University of Copenhagen in Denmark has...


EU approves Novo Nordisk’s oral semaglutide
The European Medicines Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) has approved an update to Novo Nordisk’s...


RYGB is effective in men with individualised follow-up protocols
Roux-en-Y gastric bypass (RYGB) is effective in men with obesity, demonstrating substantial excess weight loss and significant long-term...


Weekly dose of semaglutide 7.2 mg can significantly improve weight loss and related health outcomes in adults living with obesity
A higher weekly dose of semaglutide (7.2 mg) can significantly improve weight loss and related health outcomes in adults living with...
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