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Following a competitive review process, the National Institutes of Health (NIH) funding for Pennington Biomedical’s Metabolic Basis of Disease Center of Biomedical Research Excellence (COBRE) was renewed for an additional five years. This Phase II renewal builds on the momentum achieved since the center’s establishment in 2020, enabling continued support for young scientists who are focused on the mechanisms through which nutrition and metabolism contribute to health. Jackie

Higher hospital and surgeon volumes were associated with lower short-term mortality, fewer complications and shorter hospital stays, after bariatric surgery, according to researchers from Technische Universität Berlin, Berlin, Germany. The association was more pronounced in higher-quality studies. Future research should aim to standardize volume definitions to improve comparability and support policy efforts to centralize care and enhance patient outcomes. The researchers per

Body mass index (BMI) alone may not be enough to measure someone's risk of cardiometabolic disease, according to researchers at UTHealth Houston. The research, led by a team from the Border Health Research Cohort at UTHealth Houston School of Public Health, focused on the relationship between adiposity, or excess fat tissue, and cardiometabolic disease in adults. Cardiometabolic disease is a group of health problems like heart disease and diabetes that are often caused by thi

Researchers from The Institute of Cancer Research and Imperial College London have reported cancer incidence rates increased for several cancer, apart from colorectal cancer, increases occurred in both younger and older adults. The cancer types where incidence rates rose for both younger and older adults were all related to obesity. The researchers studied annual cancer incidence data from 2003 to 2017 from 42 countries in Asia, Europe, Africa, North and South America, and Au

A simple standard MRI brain scan could predict which people with mental illnesses will gain weight after their initial diagnosis, thereby increasing their risk of physical diseases, and which ones will not. Visualisation and performance of the BMI predictor. Credit: Nature Mental Health (2025). DOI: 10.1038/s44220-025-00522-3 "This would allow us to start targeted prevention against the weight gain frequently observed in this patient group," explained Professor Nikolaos Kouts

Sirona - a dual-polymer hydrogel pill - could soon offer a new and affordable weight management treatment, following a successful clinical trial involving University of Bristol researchers. Sirona developed by Oxford Medical Products is a hydrogel-based pill that is designed to aid weight loss by reducing hunger. After it is swallowed, the pill expands in your stomach, making you feel full faster. This helps you eat less without needing strong medications or injections. In th

Ascletis Pharma has completed enrolment in the US Phase IIa study for its once-monthly subcutaneous (SQ) depot formulation (treatment formulation) of small molecule GLP-1 receptor (GLP-1R) agonist ASC30 for the treatment of obesity. All 65 participants are obese or overweight with at least one weight-related comorbidity. The Phase IIa study of ASC30 once-monthly SQ depot treatment formulation is a 12-week, randomised, double-blind, placebo-controlled and multi-centre study co

Novo Nordisk has received FDA approval for Rybelsus for reducing the risk of major adverse cardiovascular events (MACE) such as cardiovascular (CV) death, heart attack, or stroke in adults with type 2 diabetes who are at high risk for these events, whether they've had a prior CV event or not (primary and secondary prevention). Results of the SOUL trial reinforce the clinical profile of the semaglutide molecule, which has been studied across a variety of therapeutic areas. "Ev

The global anti-obesity drug market is estimated to increase in valve to $25.87 billion in 2025 and is expected to reach $82.55 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 18.01% from 2025 to 2032.  This strong market growth is driven by the rising global prevalence of obesity and the increasing demand for effective pharmaceutical treatments, according to a re[ort by According to Coherent Market Insights (CMI). Additionally, advancements in drug formul

A patient’s decision to undergo bariatric surgery is often driven by a combination of complex factors such as health concerns, impaired quality of life and societal pressure, according to researchers from the University College Cork, Cork, Ireland. They found that health concerns were the primary motivator, with participants seeking to address comorbidities, mitigate health risks, and enhance their quality of life. In addition, body image, psychological well-being, and resist