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Bariatric surgery likely to generate substantial economic benefits by increasing earnings and employment opportunities
Bariatric surgery results in a sustained increase in the probability of being a paid employee from four months after surgery over the five-year follow-up period, leading to increased earnings, according to a study by UK researchers. The researchers noted that there is substantial evidence that living with obesity can affect an individual’s pay and employment however, there is little evidence on the impact of weight-management interventions, such as surgery, in improving labou


Study raises concerns over long-term effectiveness of GLP-1s
Researchers have found that people regain weight faster after quitting these GLP-1s compared with after diet and exercise alone. Improvements in heart health and diabetes risk also tend to reverse within a few years. The results suggest long-term success may require more than medication alone. The findings call into question how durable these treatments really are. On average, individuals regained about 0.4 kilograms per month after stopping medication. Based on these trends


Overweight and obesity-linked cardiovascular deaths increasing in young Australians
Higher rates of death among younger Australians from cardiovascular disease has been linked to being overweight or obese, a study by researchers at the University of Melbourne has reported. The study looked at premature overweight and obesity-related cardiovascular disease mortality for people aged between 35–74 years. Professor Tim Adair, a demographer in the Nossal Institute for Global Health at the University of Melbourne, used Australian Bureau of Statistics death certifi


BPD/DS and SADI-S show comparable short-term outcomes as revisional procedures following RYGB
Both biliopancreatic diversion with duodenal switch (BPD/DS) or single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) show comparable short-term outcomes when performed as revisional procedures following RYGB. Although overall perioperative complications did not differ between groups, the approximately 6% anastomotic leak rate observed in both cohorts highlights the greater complexity and risk inherent to revisional bariatric surgery relative to primary ope


Positive Phase II results for Genentech’s dual GLP-1/GIP CT-388 for obesity
Genentech announced positive topline results from CT388-103, a Phase II clinical trial of CT-388, an investigational dual GLP-1/GIP receptor agonist being developed for the treatment of obesity. The study found that once-weekly subcutaneous injections of CT-388 (titrated up to 24 mg) resulted in significant and clinically meaningful placebo-adjusted weight loss of 22.5% (efficacy estimand) without reaching a weight loss plateau at 48 weeks. CT-388 aims to reduce appetite and


Ring-augmented SG betters standard SG for greater weight-loss durability at 36 months
Ring-augmented sleeve gastrectomy (Ra-SG) achieved statistically greater weight-loss durability at 36 months compared with standard sleeve gastrectomy (SG), according to the outcomes from a randomised clinical trial by researchers from Egypt. They also reported that Ra-SG has a lower incidence of clinically significant RWG and smaller gastric pouch volumes at three years. According to the authors, although Ra-SG has the potential to improve SG by placing a non-adjustable ring
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